Pre Eclampsia support
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Pre Eclampsia support

For Women & their families who have suffered with Pre Eclampsia, Eclampsia, HELLP syndrome, Pregnancy induced hypertension (PIH) and related conditions.
 
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 The next pregnancy after pre eclampsia

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Suzie
New User


Posts : 4
Join date : 2008-05-27
Location : Canberra, Australia

The next pregnancy after pre eclampsia Empty
PostSubject: The next pregnancy after pre eclampsia   The next pregnancy after pre eclampsia EmptyTue 27 May 2008, 11:28 pm

Hi Liz
Thank you for setting up this forum. I had been thinking of posting on the other forum but didnít realise they were having trouble so you have saved me some time. I responded to an enquiry on the other forum where you could e-mail any questions that we had but never got a reply and canít find where it was any more but hope that you are able to find me the answer. It is more a statistical questions to help me make some very important decisions.
1. what is the chance of getting pre-eclampsia with the next pregnancy with the same partner when using
a. aspirin or
b. aspirin and heparin
2. what is the chance of getting pre-eclampsia with the next pregnancy with a different partner when using
a. aspirin or
b. aspirin and heparin
3. what is the chance of getting pre-eclampsia with the next pregnancy with a different partner and with a non family egg donor when using
a. aspirin or
b. aspirin and heparin
Just a little history I had severe pre-eclampsia with the first recognisable signs by me (in hindsight) at 26+5 weeks gestation. My son was born at 27+3 weeks gestation just over 3 years ago.
Please let me know if you require more details to answer the questions.
Take care
Suzie
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Liz Pidgley
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Liz Pidgley

Posts : 702
Join date : 2008-04-23

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PostSubject: Re: The next pregnancy after pre eclampsia   The next pregnancy after pre eclampsia EmptyWed 28 May 2008, 8:06 pm

Hi Suzie,

Welcome to the site.

Giving statistics on you as an individual is really difficult as I dont have your whole medical histories and even if I did, although I am a Registered Nurse with experience in this field, I am not a medic.
I can give you very general statistics that may help but would suggest you seek a specialists opinion to verify this in line with your own history.

The risks are as follows if you have - (reference 2)
Previous pre-eclampsia 7 times more likely of recurrance.
Antiphospholipid antibodies 10 x more likely
Diabetes 3.5 x more likely
Family history 3 x more likely
Multiple pregnancy(twins) 3 x more likely
First pregnancy 3 x more likely
Age 40 or more & already has children 2 x more likely
Age 40 or & more first pregnancy. 2 x more likely
BMI raised at booking 2 x more likely
Diastolic bp at booking 2 x more likely

There was a school of thought that felt a change of partner may change the risks and while it seems there is still some truth in that statement due to the exposure of the antigens in partners sperm it was felt that in general and change of partner coincided with a longer interval between pregnancies and in fact it was this interval that increased the risk. It is thought that an interval of 10 years or more increased the risk.

Aspirin is recommended as it in the PARIS review 'low dose aspirin offered moderate benefits of prevention of pre eclampsia & its related conditions but it could not define which sub groups benefitted most & which did not'. (1)

The use of heparin is decided by your Consultant obstetrician often in partnership with a haematologist. You will need to be tested for a variety of 'sticky blood syndromes' which is known as a Thrombophilia screen. This is likely to include conditions like Anti-phospho-lipid syndrome (APLS), thrombophilia and Leiden Factor V.

The use of heparin if indicated will mean lots of blood tests to check your blood is not too thin.

The use of donor eggs increase the risk by about 4x even if they are from a family member, eg your sister, (about 2x more likely) increase the risk of developing PE and have posted separatley about this.

I really hope all thsi helps Suzie, but if you have any more questions please do feel free to fire away! If you would prefer to keep things more confidential I am happy for you to PM me.

Best Wishes
Liz

Reference (1)
http://www.aspirin-foundation.com/suitability/documents/070531Aspirinforpre-eclampsia-revisedAFwebsitepaper.pdf

Reference (2) Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies
Kirsten Duckitt and Deborah Harrington
BMJ 2005 330: 565.
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Suzie
New User


Posts : 4
Join date : 2008-05-27
Location : Canberra, Australia

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PostSubject: Re: The next pregnancy after pre eclampsia   The next pregnancy after pre eclampsia EmptyThu 29 May 2008, 3:03 am

Hi Liz
That really helps a lot. Thank you. It is so difficult to be well informed with pre-eclampsia when so little is known about it. It is also very difficult to find a good specialist in my location. I've had to do all my own research and got my GP to do all the blood tests.
As my situation is unique I'll PM you with some more information.
Take care
Suzie
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Liz Pidgley
Admin
Liz Pidgley

Posts : 702
Join date : 2008-04-23

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PostSubject: Re: The next pregnancy after pre eclampsia   The next pregnancy after pre eclampsia EmptyThu 29 May 2008, 7:59 am

Hi Suzie,

Im glad we can be of help.
I have just noticed where you are posting from - I thought you were just up very late at night! (Ooops!)
Did you know that there is an Australian Pre Eclamspia Support organisation?
It called AAPEC - Australian Action on Pre Eclampsia. They may well be able to support you to find a specialist nearer your locality.

Their link is - http://www.aapec.org.au/
I am just about to read your PM!
Best Wishes
Liz
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http://www.preeclampsiasupport.com
Suzie
New User


Posts : 4
Join date : 2008-05-27
Location : Canberra, Australia

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PostSubject: Re: The next pregnancy after pre eclampsia   The next pregnancy after pre eclampsia EmptyTue 17 Jun 2008, 11:48 pm

Hi Liz
I am a member already and they are a great support but do not at this stage have the resources to have a forum like this. It is so great to have our questions answered so quickly. flower
Since your PM I have gotten advice from them on a specialist here so I am in the process of getting a referral. Hopefully my Dr will not have a problem with it. It has already taken me a week just to get to see her and then the specialist only has a few spots left for July which might have already been filled so I might have to wait until August. I guess I am lucky as if it was a private specialist I might have to wait months.
Thank you again for all your help.
Take care
Suzie
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